Structure and activation mechanism of the BBSome membrane protein trafficking complex.

Singh, Sandeep K; Gui, Miao; Koh, Fujiet; Yip, Matthew Cj; Brown, Alan

Singh, Sandeep K; Gui, Miao; Koh, Fujiet; Yip, Matthew Cj; Brown, Alan.

Afiliação

Singh SK; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, United States.
Gui M; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, United States.
Koh F; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, United States.
Yip MC; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, United States.
Brown A; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, United States.

Elife ; 92020 01 15.

Article em En | MEDLINE | ID: mdl-31939736

Assuntos

Fatores de Ribosilação do ADP/metabolismo; Proteínas de Membrana/metabolismo; Animais; Síndrome de Bardet-Biedl/metabolismo; Bovinos; Cílios/metabolismo; Microscopia Crioeletrônica; Humanos; Ligação Proteica; Conformação Proteica; Domínios Proteicos; Transporte Proteico

Palavras-chave

BBSome; Bos taurus; cilia; cryo-EM; intraflagellar transport; molecular biophysics; protein trafficking; structural biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Ribosilação do ADP / Proteínas de Membrana Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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