Protection of cattle against rinderpest with vaccinia virus recombinants expressing the HA or F gene.
Science
; 242(4881): 1058-61, 1988 Nov 18.
Article
em En
| MEDLINE
| ID: mdl-3194758
ABSTRACT
Rinderpest is a highly contagious ruminant viral disease manifested by a rapid course and greater than 90% mortality. Infectious vaccinia virus recombinants were constructed that express either the hemagglutinin or the fusion gene of rinderpest virus. All cattle vaccinated with either recombinant or with the combined recombinants produced neutralizing antibodies against rinderpest virus and were protected against the disease when challenged with more than 1000 times the lethal dose of the virus.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peste Bovina
/
Vacinas
/
Vacinas Sintéticas
/
Proteínas Virais de Fusão
/
Hemaglutininas Virais
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article