Chitin/chitosan derivatives and their interactions with microorganisms: a comprehensive review and future perspectives.
Crit Rev Biotechnol
; 40(3): 365-379, 2020 May.
Article
em En
| MEDLINE
| ID: mdl-31948287
ABSTRACT
Chitosan, obtained as a result of the deacetylation of chitin, one of the most important naturally occurring polymers, has antimicrobial properties against fungi, and bacteria. It is also useful in other fields, including food, biomedicine, biotechnology, agriculture, and the pharmaceutical industries. A literature survey shows that its antimicrobial activity depends upon several factors such as the pH, temperature, molecular weight, ability to chelate metals, degree of deacetylation, source of chitosan, and the type of microorganism involved. This review will focus on the in vitro and in vivo antimicrobial properties of chitosan and its derivatives, along with a discussion on its mechanism of action during the treatment of infectious animal diseases, as well as its importance in food safety. We conclude with a summary of the challenges associated with the uses of chitosan and its derivatives.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Quitina
/
Quitosana
/
Anti-Infecciosos
Limite:
Animals
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article