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Novel Alzheimer risk genes determine the microglia response to amyloid-ß but not to TAU pathology.
Sierksma, Annerieke; Lu, Ashley; Mancuso, Renzo; Fattorelli, Nicola; Thrupp, Nicola; Salta, Evgenia; Zoco, Jesus; Blum, David; Buée, Luc; De Strooper, Bart; Fiers, Mark.
Afiliação
  • Sierksma A; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Lu A; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
  • Mancuso R; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Fattorelli N; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
  • Thrupp N; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Salta E; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
  • Zoco J; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Blum D; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
  • Buée L; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • De Strooper B; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
  • Fiers M; VIB Center for Brain & Disease Research, Leuven, Belgium.
EMBO Mol Med ; 12(3): e10606, 2020 03 06.
Article em En | MEDLINE | ID: mdl-31951107
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Proteínas tau / Microglia / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Proteínas tau / Microglia / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article