Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1&#945; and fatty acid metabolism in skeletal muscle.

So, Wai-Kin; Kim, Hyoung Kyu; Chen, Yingxian; Jeong, Seung Hun; Yeung, Patrick Ka Kit; Chow, Billy C K; Han, Jin; Chung, Sookja K

Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1α and fatty acid metabolism in skeletal muscle.

So, Wai-Kin; Kim, Hyoung Kyu; Chen, Yingxian; Jeong, Seung Hun; Yeung, Patrick Ka Kit; Chow, Billy C K; Han, Jin; Chung, Sookja K.

Afiliação

So WK; School of Biomedical Sciences, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Kim HK; National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Project Team, College of Medicine, Cardiovascular and Metabolic Disease Center Inje University, Busan, South Korea.
Chen Y; School of Biomedical Sciences, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Jeong SH; National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Project Team, College of Medicine, Cardiovascular and Metabolic Disease Center Inje University, Busan, South Korea.
Yeung PKK; School of Biomedical Sciences, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Chow BCK; School of Biological Sciences, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Han J; National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Project Team, College of Medicine, Cardiovascular and Metabolic Disease Center Inje University, Busan, South Korea. phyhan@inje.ac.kr.
Chung SK; Macau University of Science and Technology, Faculty of Medicine, Taipa, Macau. skchung@must.edu.mo.

Pflugers Arch ; 472(2): 195-216, 2020 02.

Article em En | MEDLINE | ID: mdl-31955265

Assuntos

Ácidos Graxos/metabolismo; Fatores de Troca do Nucleotídeo Guanina/metabolismo; Atividade Motora; Músculo Esquelético/metabolismo; Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo/metabolismo; Estresse Fisiológico; Animais; Fatores de Troca do Nucleotídeo Guanina/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Músculo Esquelético/fisiologia; Esforço Físico

Palavras-chave

Exchange protein directly activated by cAMP (Epac); Exercise capacity; Fatty acid metabolism; PGC-1α; Skeletal muscle

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Músculo Esquelético / Fatores de Troca do Nucleotídeo Guanina / Ácidos Graxos / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Atividade Motora Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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