Isoalantolactone restores the sensitivity of gram-negative Enterobacteriaceae carrying MCR-1 to carbapenems.

Lu, Na; Lv, Qianghua; Sun, Xiaodi; Zhou, Yonglin; Guo, Yan; Qiu, Jiazhang; Zhang, Peng; Wang, Jianfeng

Lu, Na; Lv, Qianghua; Sun, Xiaodi; Zhou, Yonglin; Guo, Yan; Qiu, Jiazhang; Zhang, Peng; Wang, Jianfeng.

Afiliação

Lu N; Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun, China.
Lv Q; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Sun X; Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun, China.
Zhou Y; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Guo Y; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Qiu J; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Zhang P; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Wang J; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.

J Cell Mol Med ; 24(4): 2475-2483, 2020 02.

Article em En | MEDLINE | ID: mdl-31957212

Assuntos

Proteínas de Bactérias/metabolismo; Carbapenêmicos/farmacologia; Enterobacteriaceae/efeitos dos fármacos; Enterobacteriaceae/metabolismo; Sesquiterpenos/farmacologia; Animais; Antibacterianos/farmacologia; Escherichia coli/efeitos dos fármacos; Escherichia coli/metabolismo; Infecções por Escherichia coli/tratamento farmacológico; Feminino; Infecções por Klebsiella/tratamento farmacológico; Klebsiella pneumoniae/efeitos dos fármacos; Klebsiella pneumoniae/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Testes de Sensibilidade Microbiana/métodos; Polimixina B/farmacologia

Palavras-chave

mcr-1; isoalantolactone; polycolistin B; synergistic effect

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Proteínas de Bactérias / Carbapenêmicos / Enterobacteriaceae Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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