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Developing an Executive Functioning Composite Score for Research and Clinical Trials.
Iverson, Grant L; Karr, Justin E; Terry, Douglas P; Garcia-Barrera, Mauricio A; Holdnack, James A; Ivins, Brian J; Silverberg, Noah D.
Afiliação
  • Iverson GL; Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Spaulding Research Institute, and Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, MA 02129, USA.
  • Karr JE; Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Spaulding Research Institute, and Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, MA 02129, USA.
  • Terry DP; Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Spaulding Research Institute, and Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, MA 02129, USA.
  • Garcia-Barrera MA; Department of Psychology, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada.
  • Holdnack JA; Research and Statistics Consultant, Bear, DE 19701, USA.
  • Ivins BJ; Defense and Veterans Brain Injury Center, Silver Spring, MD 20910, USA.
  • Silverberg ND; Division of Physical Medicine and Rehabilitation, University of British Columbia; Rehabilitation Research Program, GF Strong Rehab Centre, Vancouver, British Columbia V5Z 2G9, Canada.
Arch Clin Neuropsychol ; 35(3): 312-325, 2020 Apr 20.
Article em En | MEDLINE | ID: mdl-31965141
OBJECTIVE: Executive functioning encompasses interactive cognitive processes such as planning, organization, set-shifting, inhibition, self-monitoring, working memory, and initiating and sustaining motor and mental activity. Researchers therefore typically assess executive functioning with multiple tests, each yielding multiple scores. A single composite score of executive functioning, which summarizes deficits across a battery of tests, would be useful in research and clinical trials. This study examines multiple candidate composite scores of executive functioning using tests from the Delis-Kaplan Executive Function System (D-KEFS). METHOD: Participants were 875 adults between the ages of 20 and 89 years from the D-KEFS standardization sample. Seven Total Achievement scores were used from three tests (i.e., Trail Making, Verbal Fluency, and Color-Word Interference) to form eight composite scores that were compared based on their psychometric properties and association with intelligence (IQ). RESULTS: The distributions of most composite scores were mildly to severely skewed, and some had a pronounced ceiling effect. The composite scores all showed a medium positive correlation with IQ. The composite scores were highly intercorrelated in the total sample and in four IQ subgroups (i.e., IQ <89, 90-99, 100-109, 110+), with some being so highly correlated that they appear redundant. CONCLUSIONS: This study is part of a larger research program developing a cognition endpoint for research and clinical trials with sound psychometric properties and utility across discrepant test batteries. Future research is needed to examine the reliability and ecological validity of these composite scores.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Função Executiva / Inteligência / Testes Neuropsicológicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Função Executiva / Inteligência / Testes Neuropsicológicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article