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VEGF-B ablation in pancreatic ß-cells upregulates insulin expression without affecting glucose homeostasis or islet lipid uptake.
Ning, Frank Chenfei; Jensen, Nina; Mi, Jiarui; Lindström, William; Balan, Mirela; Muhl, Lars; Eriksson, Ulf; Nilsson, Ingrid; Nyqvist, Daniel.
Afiliação
  • Ning FC; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Jensen N; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Mi J; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Lindström W; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Balan M; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Muhl L; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Eriksson U; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Nilsson I; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Nyqvist D; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden. daniel.nyqvist@ki.se.
Sci Rep ; 10(1): 923, 2020 01 22.
Article em En | MEDLINE | ID: mdl-31969592
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Fator B de Crescimento do Endotélio Vascular / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Ácidos Graxos / Glucose / Homeostase / Insulina Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Fator B de Crescimento do Endotélio Vascular / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Ácidos Graxos / Glucose / Homeostase / Insulina Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article