Low-intensity pulsed ultrasound inhibits VEGFA expression in chondrocytes and protects against cartilage degeneration in experimental osteoarthritis.

Guan, Mengtong; Zhu, Ying; Liao, Bo; Tan, Qiaoyan; Qi, Huabing; Zhang, Bin; Huang, Junlan; Du, Xiaolan; Bai, Dingqun

Guan, Mengtong; Zhu, Ying; Liao, Bo; Tan, Qiaoyan; Qi, Huabing; Zhang, Bin; Huang, Junlan; Du, Xiaolan; Bai, Dingqun.

Afiliação

Guan M; Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, China.
Zhu Y; Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, China.
Liao B; Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, China.
Tan Q; Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Qi H; Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhang B; Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Huang J; Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Du X; Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Bai D; Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, China.

FEBS Open Bio ; 10(3): 434-443, 2020 03.

Article em En | MEDLINE | ID: mdl-31975545

Assuntos

Cartilagem/metabolismo; Condrócitos/metabolismo; Terapia por Ultrassom/métodos; Fator A de Crescimento do Endotélio Vascular/metabolismo; Animais; Cartilagem/fisiologia; Doenças das Cartilagens/metabolismo; Cartilagem Articular/metabolismo; Matriz Extracelular/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Osteoartrite/metabolismo; Osteoartrite/fisiopatologia; Osteófito/metabolismo; Substâncias Protetoras/metabolismo; Substâncias Protetoras/farmacologia; Sinovite/metabolismo; Ondas Ultrassônicas; Fator A de Crescimento do Endotélio Vascular/fisiologia; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo; Proteínas Quinases p38 Ativadas por Mitógeno/farmacologia

Palavras-chave

articular cartilage; low-intensity pulsed ultrasound; osteoarthritis; vascular endothelium growth factor A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia por Ultrassom / Cartilagem / Condrócitos / Fator A de Crescimento do Endotélio Vascular Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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