Reduction in plasma norepinephrine during fenfluramine treatment.
Clin Pharmacol Ther
; 21(2): 216-21, 1977 Feb.
Article
em En
| MEDLINE
| ID: mdl-319936
ABSTRACT
Plasma norepinephrine levels were reduced to 30% of placebo levels during the administration of fenfluramine, 120 mg/day, for 10 or more days. There was also a significant reduction in plasma dopamine beta-hydroxylase activity during fenfluramine treatment, suggesting that chronic administration may induce antiadrenergic effects which may be useful in the treatment of disorders affected by circulating catecholamines.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Norepinefrina
/
Fenfluramina
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1977
Tipo de documento:
Article