Metallation-Induced Heterogeneous Dynamics of DNA Revealed by Single-Molecule FRET.

Berrocal-Martin, Raul; Sanchez-Cano, Carlos; Chiu, Cookson K C; Needham, Russell J; Sadler, Peter J; Magennis, Steven W

Berrocal-Martin, Raul; Sanchez-Cano, Carlos; Chiu, Cookson K C; Needham, Russell J; Sadler, Peter J; Magennis, Steven W.

Afiliação

Berrocal-Martin R; School of Chemistry, University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK.
Sanchez-Cano C; Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL, UK.
Chiu CKC; Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL, UK.
Needham RJ; Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL, UK.
Sadler PJ; Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL, UK.
Magennis SW; School of Chemistry, University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK.

Chemistry ; 26(22): 4980-4987, 2020 Apr 16.

Article em En | MEDLINE | ID: mdl-31999015

Assuntos

Antineoplásicos/química; DNA/química; Antineoplásicos/farmacologia; DNA/metabolismo; Fluorescência; Transferência Ressonante de Energia de Fluorescência; Nanotecnologia; Conformação de Ácido Nucleico

Palavras-chave

DNA; FRET; metallodrugs; organo-osmium complexes; single-molecule studies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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