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The prevention and management of asparaginase-related venous thromboembolism in adults: Guidance from the SSC on Hemostasis and Malignancy of the ISTH.
Zwicker, Jeffrey I; Wang, Tzu-Fei; DeAngelo, Daniel J; Lauw, Mandy N; Connors, Jean M; Falanga, Anna; McMasters, Malgorzata; Carrier, Marc.
Afiliação
  • Zwicker JI; Division of Hematology and Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Wang TF; Division of Hematology, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • DeAngelo DJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lauw MN; Department of Hematology, Erasmus MC, Rotterdam, the Netherlands.
  • Connors JM; Department of Hematology, Amsterdam UMC, Amsterdam, the Netherlands.
  • Falanga A; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Amsterdam, the Netherlands.
  • McMasters M; Hematology Division, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Carrier M; University of Milan Bicocca, Milan, Italy.
J Thromb Haemost ; 18(2): 278-284, 2020 02.
Article em En | MEDLINE | ID: mdl-31999063
Venous thromboembolism is a common complication of asparaginase-based chemotherapy regimens for the treatment of acute lymphoblastic leukemia. Thrombosis associated with asparaginase administration poses a number of specific and often clinically challenging management decisions. This review provides guidance on the prevention and treatment of thrombosis associated with asparaginase in adults including discussions on antithrombin repletion, pharmacologic thromboprophylaxis, cerebral venous thrombosis, and therapeutic anticoagulation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Tromboembolia Venosa Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Tromboembolia Venosa Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article