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Revealing an Internal Stabilization Deficiency in the DNA Polymerase ß K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Batra, Vinod K; Alnajjar, Khadijeh S; Sweasy, Joann B; McKenna, Charles E; Goodman, Myron F; Wilson, Samuel H.
Afiliação
  • Batra VK; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T. W. Alexander Drive, Research Triangle Park, North Carolina 27709, United States.
  • Alnajjar KS; Department of Therapeutic Radiology and Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, United States.
  • Sweasy JB; Department of Therapeutic Radiology and Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, United States.
  • McKenna CE; Department of Chemistry, University of Southern California, Los Angeles, California 90089-1062, United States.
  • Goodman MF; Department of Biological Sciences, University of Southern California, Los Angeles, California 90089-0371, United States.
  • Wilson SH; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T. W. Alexander Drive, Research Triangle Park, North Carolina 27709, United States.
Biochemistry ; 59(8): 955-963, 2020 03 03.
Article em En | MEDLINE | ID: mdl-31999437
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Polimerase beta Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Polimerase beta Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article