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Continued misuse of orphan drug legislation: a life-threatening risk for mexiletine.
Postema, Pieter G; Schwartz, Peter J; Arbelo, Elena; Bannenberg, Wilbert J; Behr, Elijah R; Belhassen, Bernard; Brugada, Josep; Brugada, Pedro; John Camm, A; Casado-Arroyo, Ruben; 't Hoen, Ellen; Hollak, Carla E M; Kääb, Stefan; Lambiase, Pier D; Leenhardt, Antoine; Priori, Silvia G; Probst, Vincent; Stunnenberg, Bas C; Tfelt-Hansen, Jacob; Van Engelen, Baziel G M; Veltmann, Christian; Viskin, Sami; Wilde, Arthur A M.
Afiliação
  • Postema PG; Department of Cardiology, Heart Center, Amsterdam University Medical Centers, Academic Medical Center, PO-Box 22700, 1100DE, Amsterdam, The Netherlands, Member of the European Reference Network (ERN) GUARD-Heart.
  • Schwartz PJ; Instituto Auxologico Italiano, IRCCS, Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy. Member of the European Reference Network (ERN) GUARD-Heart.
  • Arbelo E; Arrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona and Institut d'Investigació August Pi i Sunyer (IDIBAPS), Barcelona, Spain, and Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
  • Bannenberg WJ; Pharmaceutical Accountability Foundation, The Netherlands.
  • Behr ER; Cardiology Clinical Academic Group, Institute of Molecular and Clinical Sciences, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, London, UK. Member of the European Reference Network (ERN) GUARD-Heart.
  • Belhassen B; Heart Institute, Hadassah University Hospital, Jerusalem, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Brugada J; Cardiology Department, Hospital Clinic, University of Barcelona, Barcelona, Spain.
  • Brugada P; Cardiovascular Division, Free University of Brussels, Brussels, Belgium.
  • John Camm A; Cardiology Clinical Academic Group, Molecular & Clinical Sciences Institute, St, George's University of London, London, UK.
  • Casado-Arroyo R; Department of Cardiology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • 't Hoen E; Medicines Law & Policy, Amsterdam, The Netherlands, and Global Health Unit, University Medical Centre Groningen, The Netherlands.
  • Hollak CEM; Department of Endocrinology and Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Kääb S; Department of Medicine I, University Hospital Munich, Campus Großhadern, Ludwig-Maximilians University Munich (LMU), Munich, Germany, and DZHK (German Centre for Cardiovascular Research), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany.
  • Lambiase PD; Electrophysiology Department, Barts Heart Centre, Barts Health NHS trust, London, UK. Member of the European Reference Network (ERN) GUARD-Heart.
  • Leenhardt A; Unité de Rythmologie, Centre de Référence Maladies Cardiaques Héréditaires, Service de Cardiologie, Université de Paris, AP-HP Hôpital Bichat, Paris, France. Member of the European Reference Network (ERN) GUARD-Heart.
  • Priori SG; Department of Molecular Medicine University of Pavia, Cardiology & Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy. Member of the European Reference Network (ERN) GUARD-Heart.
  • Probst V; L'institut du thorax, service de cardiologie du CHU de Nantes, Nantes, France. Member of the European Reference Network (ERN) GUARD-Heart.
  • Stunnenberg BC; Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Tfelt-Hansen J; Department of Cardiology, Heart Centre, Copenhagen University Hospital, Rigshospitalet, and Department of Forensic Medicine, Faculty of Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Member of the European Reference Network (ERN) GUARD-Heart.
  • Van Engelen BGM; Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Veltmann C; Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
  • Viskin S; Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Wilde AAM; Department of Cardiology, Heart Center, Amsterdam University Medical Centers, Amsterdam, The Netherlands. Member of the European Reference Network (ERN) GUARD-Heart.
Eur Heart J ; 41(5): 614-617, 2020 02 01.
Article em En | MEDLINE | ID: mdl-32006435
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Legislação de Medicamentos / Mexiletina Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Legislação de Medicamentos / Mexiletina Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article