Reciprocal Regulatory Interaction between TRPV1 and Kinin B1 Receptor in a Rat Neuropathic Pain Model.

Cernit, Veronica; Sénécal, Jacques; Othman, Rahmeh; Couture, Réjean

Cernit, Veronica; Sénécal, Jacques; Othman, Rahmeh; Couture, Réjean.

Afiliação

Cernit V; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Sénécal J; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Othman R; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Couture R; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada.

Int J Mol Sci ; 21(3)2020 Jan 27.

Article em En | MEDLINE | ID: mdl-32012798

Assuntos

Neuralgia/etiologia; Neuralgia/metabolismo; Receptor B1 da Bradicinina/metabolismo; Canais de Cátion TRPV/metabolismo; Animais; Astrócitos/metabolismo; Antagonistas de Receptor B1 da Bradicinina/farmacologia; Modelos Animais de Doenças; Gânglios Espinais/metabolismo; Neuralgia/fisiopatologia; Dor Nociceptiva; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ratos; Medula Espinal/metabolismo

Palavras-chave

B1 receptor; TRPV1; allodynia; astrocytes; bradykinin; cytokines; dorsal root ganglion; hyperalgesia; sensory fibers; spinal cord

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor B1 da Bradicinina / Canais de Cátion TRPV / Neuralgia Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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