The Interplay of the Extracellular Matrix and Stromal Cells as a Drug Target in Stroma-Rich Cancers.

Kozlova, Nina; Grossman, Joseph E; Iwanicki, Marcin P; Muranen, Taru

Kozlova, Nina; Grossman, Joseph E; Iwanicki, Marcin P; Muranen, Taru.

Afiliação

Kozlova N; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Grossman JE; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Iwanicki MP; Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ, USA.
Muranen T; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. Electronic address: tmuranen@bidmc.harvard.edu.

Trends Pharmacol Sci ; 41(3): 183-198, 2020 03.

Article em En | MEDLINE | ID: mdl-32014341

Assuntos

Neoplasias; Preparações Farmacêuticas; Matriz Extracelular; Humanos; Neoplasias/tratamento farmacológico; Células Estromais; Microambiente Tumoral

Palavras-chave

cancer-associated fibroblasts; clinical trials; drug resistance; extracellular matrix; stroma-cancer crosstalk; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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