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Genes and environment in attachment.
Picardi, Angelo; Giuliani, Eugenia; Gigantesco, Antonella.
Afiliação
  • Picardi A; Centre for Behavioural Sciences and Mental Health, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy. Electronic address: angelo.picardi@iss.it.
  • Giuliani E; Department of Molecular Medicine, Sapienza University, Viale Regina Elena, 291-293, 00161 Rome, Italy.
  • Gigantesco A; Centre for Behavioural Sciences and Mental Health, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy.
Neurosci Biobehav Rev ; 112: 254-269, 2020 05.
Article em En | MEDLINE | ID: mdl-32014527
In the last two decades, there has been increasing research interest in disentangling the contribution of genetic and environmental factors to individual differences in attachment, and in identifying the genes involved in shaping attachment. Twin studies suggest that as attachment changes during the course of development, genetic factors may play a progressively more important role, while shared environmental effects might decrease. However, most of this literature is limited by low power, measurement issues, and cross-sectional design. The findings of molecular genetic studies are, overall, inconclusive. The literature on main genetic effects and gene-by-environment interactions on attachment is filled with inconsistent and unreplicated findings. Also, most studies are underpowered. Challenges for future research are to identify the unshared environmental mechanisms involved in shaping attachment, and to better elucidate the genes involved and their interaction with the environment. Some pioneer studies suggested that the incorporation of epigenetic processes into G × E interaction models might represent a promising future way for investigating the complex, dynamic interplay between genes, environment, and attachment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epigênese Genética / Interação Gene-Ambiente / Individualidade / Apego ao Objeto Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epigênese Genética / Interação Gene-Ambiente / Individualidade / Apego ao Objeto Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article