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Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain.
Lundgren, Jolanta L; Vandermeulen, Lina; Sandebring-Matton, Anna; Ahmed, Saheeb; Winblad, Bengt; Di Luca, Monica; Tjernberg, Lars O; Marcello, Elena; Frykman, Susanne.
Afiliação
  • Lundgren JL; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
  • Vandermeulen L; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
  • Sandebring-Matton A; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
  • Ahmed S; Department of Diagnostic and Interventional Radiology, University Medical Center, Göttingen, Germany.
  • Winblad B; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
  • Di Luca M; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
  • Tjernberg LO; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
  • Marcello E; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
  • Frykman S; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden. susanne.frykman@ki.se.
BMC Neurosci ; 21(1): 6, 2020 02 04.
Article em En | MEDLINE | ID: mdl-32019490
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Ácido Aspártico Endopeptidases / Precursor de Proteína beta-Amiloide / Secretases da Proteína Precursora do Amiloide / Proteína ADAM10 / Proteínas de Membrana / Neurônios Limite: Aged / Aged80 / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Ácido Aspártico Endopeptidases / Precursor de Proteína beta-Amiloide / Secretases da Proteína Precursora do Amiloide / Proteína ADAM10 / Proteínas de Membrana / Neurônios Limite: Aged / Aged80 / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article