Utilizing the CF<sub>2</sub>H moiety as a H-bond-donating group in drug discovery.

Zafrani, Yossi; Saphier, Sigal; Gershonov, Eytan

Utilizing the CF₂H moiety as a H-bond-donating group in drug discovery.

Zafrani, Yossi; Saphier, Sigal; Gershonov, Eytan.

Afiliação

Zafrani Y; The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona 74100, Israel.
Saphier S; The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona 74100, Israel.
Gershonov E; The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona 74100, Israel.

Future Med Chem ; 12(5): 361-365, 2020 03.

Article em En | MEDLINE | ID: mdl-32027173

Assuntos

Descoberta de Drogas; Hidrocarbonetos Fluorados/química; Ligação de Hidrogênio

Palavras-chave

bioisostere; difluoromethyl; drug design; hydrogen bond

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Descoberta de Drogas / Hidrocarbonetos Fluorados Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google