Progesterone receptor heterogeneity and endometrial tumour differentiation.
Cancer Lett
; 43(3): 215-8, 1988 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-3203339
ABSTRACT
Progesterone binding components were isolated using fast protein liquid chromatography (FPLC) with a recovery efficiency of between 60-70%. In normal uterine cytosol, the two components were in about equal proportions. In endometrial cancer, the ratio of peak size between peaks 1 and 2 was 1.5 for Grade I, 3.7 for Grade II and 2.5 for Grade III. Whether estimation of the levels of the two progesterone components separately would enhance predictability of response to hormone therapy in endometrial cancer remains to be established.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uterinas
/
Receptores de Progesterona
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article