The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study.

Ma, Yuxiang; Xin, Shuang; Lin, Qingguang; Zhuang, Wei; Zhao, Yuanyuan; Zhu, Xia; Zhao, Hongyun; Huang, Min; Xun, Xu; Yang, Yunpeng; Fang, Wenfeng; Zhang, Li; Wang, Xueding

Ma, Yuxiang; Xin, Shuang; Lin, Qingguang; Zhuang, Wei; Zhao, Yuanyuan; Zhu, Xia; Zhao, Hongyun; Huang, Min; Xun, Xu; Yang, Yunpeng; Fang, Wenfeng; Zhang, Li; Wang, Xueding.

Afiliação

Ma Y; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Xin S; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510060, China.
Lin Q; BGI-Shenzhen, Shenzhen 518083, China.
Zhuang W; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Zhao Y; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510060, China.
Zhu X; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Zhao H; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510060, China.
Huang M; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Xun X; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510060, China.
Yang Y; BGI-Shenzhen, Shenzhen 518083, China.
Fang W; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Zhang L; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Wang X; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.

Ann Transl Med ; 7(24): 806, 2019 Dec.

Article em En | MEDLINE | ID: mdl-32042822

Palavras-chave

ABCB1; Non-small cell lung cancer (NSCLC); gefitinib; pharmacokinetic; single nucleotide polymorphisms (SNPs)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google