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Clinical Features and Outcomes of Bloodstream Infections Caused by New Delhi Metallo-ß-Lactamase-Producing Enterobacterales During a Regional Outbreak.
Falcone, Marco; Tiseo, Giusy; Antonelli, Alberto; Giordano, Cesira; Di Pilato, Vincenzo; Bertolucci, Pietro; Parisio, Eva Maria; Leonildi, Alessandro; Aiezza, Noemi; Baccani, Ilaria; Tagliaferri, Enrico; Righi, Lorenzo; Forni, Silvia; Sani, Spartaco; Mechi, Maria Teresa; Pieralli, Filippo; Barnini, Simona; Rossolini, Gian Maria; Menichetti, Francesco.
Afiliação
  • Falcone M; Infectious Disease Unit, Azienda Ospedaliera Universitaria Pisana, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Tiseo G; Infectious Disease Unit, Azienda Ospedaliera Universitaria Pisana, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Antonelli A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Giordano C; Microbiology Unit, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
  • Di Pilato V; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Bertolucci P; Faculty of Medicine, University of Pisa, Pisa, Italy.
  • Parisio EM; Operative Unit of Chemical-Clinical and Microbiological Analysis, San Luca Hospital, Lucca, Italy.
  • Leonildi A; Faculty of Medicine, University of Pisa, Pisa, Italy.
  • Aiezza N; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Baccani I; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Tagliaferri E; Infectious Diseases Unit, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
  • Righi L; Quality of Care and Clinical Networks, Tuscany Region, Italy.
  • Forni S; Agenzia Regionale di Sanità della Toscana, Florence, Italy.
  • Sani S; Infectious Disease Unit, Livorno Hospital, Livorno, Italy.
  • Mechi MT; Quality of Care and Clinical Networks, Tuscany Region, Italy.
  • Pieralli F; Intermediate Care Unit, Florence Careggi University Hospital, Florence, Italy.
  • Barnini S; Microbiology Unit, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
  • Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Menichetti F; Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy.
Open Forum Infect Dis ; 7(2): ofaa011, 2020 Feb.
Article em En | MEDLINE | ID: mdl-32042848
ABSTRACT
Limited data about New Delhi metallo-ß-lactamase (NDM) bacteremia are available. Blood isolates from 40 patients with NDM bacteremia were studied for antibiotic susceptibility and whole-genomic sequencing. NDM bacteremia has high 30-day mortality. In most cases, aztreonam-avibactam is active in vitro. Ceftazidime-avibactam plus aztreonam may represent a feasible therapeutic option.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article