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(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity.
Humbert, Nicolas; Kovalenko, Lesia; Saladini, Francesco; Giannini, Alessia; Pires, Manuel; Botzanowski, Thomas; Cherenok, Sergiy; Boudier, Christian; Sharma, Kamal K; Real, Eleonore; Zaporozhets, Olga A; Cianférani, Sarah; Seguin-Devaux, Carole; Poggialini, Federica; Botta, Maurizio; Zazzi, Maurizio; Kalchenko, Vitaly I; Mori, Mattia; Mély, Yves.
Afiliação
  • Humbert N; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Kovalenko L; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Saladini F; Department of Chemistry, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
  • Giannini A; Department of Medical Biotechnologies, University of Siena, viale Mario Bracci no. 16, 53100 Siena, Italy.
  • Pires M; Department of Medical Biotechnologies, University of Siena, viale Mario Bracci no. 16, 53100 Siena, Italy.
  • Botzanowski T; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Cherenok S; Laboratoire de Spectrométrie de Masse BioOrganique, IPHC UMR 7178 CNRS, Université de Strasbourg, 67000 Strasbourg, France.
  • Boudier C; Institute of Organic Chemistry, National Academy of Science of Ukraine, Murmanska str. 5, Kyiv 02660, Ukraine.
  • Sharma KK; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Real E; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Zaporozhets OA; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
  • Cianférani S; Department of Chemistry, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
  • Seguin-Devaux C; Laboratoire de Spectrométrie de Masse BioOrganique, IPHC UMR 7178 CNRS, Université de Strasbourg, 67000 Strasbourg, France.
  • Poggialini F; Department of Infection and Immunity, Luxembourg Institute of Health, 29 rue Henri Koch, L-4354 Esch-sur-Alzette, Luxembourg.
  • Botta M; Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018-2022 Università degli Studi di Siena, via Aldo Moro 2, I-53019 Siena, Italy.
  • Zazzi M; Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018-2022 Università degli Studi di Siena, via Aldo Moro 2, I-53019 Siena, Italy.
  • Kalchenko VI; Department of Medical Biotechnologies, University of Siena, viale Mario Bracci no. 16, 53100 Siena, Italy.
  • Mori M; Institute of Organic Chemistry, National Academy of Science of Ukraine, Murmanska str. 5, Kyiv 02660, Ukraine.
  • Mély Y; Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018-2022 Università degli Studi di Siena, via Aldo Moro 2, I-53019 Siena, Italy.
ACS Infect Dis ; 6(4): 687-702, 2020 04 10.
Article em En | MEDLINE | ID: mdl-32045204
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Chaperonas Moleculares / Fármacos Anti-HIV / Proteínas do Nucleocapsídeo / Calixarenos / Organofosfonatos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Chaperonas Moleculares / Fármacos Anti-HIV / Proteínas do Nucleocapsídeo / Calixarenos / Organofosfonatos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article