Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.

Reeves, Stephen R; Barrow, Kaitlyn A; Rich, Lucille M; White, Maria P; Shubin, Nicholas J; Chan, Christina K; Kang, Inkyung; Ziegler, Steven F; Piliponsky, Adrian M; Wight, Thomas N; Debley, Jason S

Reeves, Stephen R; Barrow, Kaitlyn A; Rich, Lucille M; White, Maria P; Shubin, Nicholas J; Chan, Christina K; Kang, Inkyung; Ziegler, Steven F; Piliponsky, Adrian M; Wight, Thomas N; Debley, Jason S.

Afiliação

Reeves SR; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, WA, United States.
Barrow KA; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.
Rich LM; Department of Pediatrics, University of Washington, Seattle, WA, United States.
White MP; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.
Shubin NJ; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.
Chan CK; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.
Kang I; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.
Ziegler SF; Matrix Biology Program, Benaroya Research Institute, Seattle, WA, United States.
Piliponsky AM; Matrix Biology Program, Benaroya Research Institute, Seattle, WA, United States.
Wight TN; Immunology Program, Benaroya Research Institute, Seattle, WA, United States.
Debley JS; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, United States.

Front Immunol ; 10: 3159, 2019.

Article em En | MEDLINE | ID: mdl-32047499

Assuntos

Matriz Extracelular/imunologia; Fibroblastos; Ácido Hialurônico/metabolismo; Mastócitos; Infecções por Vírus Respiratório Sincicial/imunologia; Adesão Celular/imunologia; Células Cultivadas; Quimases/biossíntese; Técnicas de Cocultura; Matriz Extracelular/química; Matriz Extracelular/metabolismo; Fibroblastos/imunologia; Fibroblastos/metabolismo; Fibroblastos/virologia; Humanos; Pulmão/imunologia; Pulmão/virologia; Mastócitos/imunologia; Mastócitos/metabolismo; Vírus Sincicial Respiratório Humano; Triptases/biossíntese

Palavras-chave

airway inflammation; airway remodeling; extracellular matrix; human lung fibroblasts; hyaluronan; mast cells; respiratory syncytial virus; tumor necrosis factor-stimulated gene 6

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Vírus Respiratório Sincicial / Matriz Extracelular / Fibroblastos / Ácido Hialurônico / Mastócitos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google