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Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent.
Fujita, Nobuhiro; Nishie, Akihiro; Asayama, Yoshiki; Ishigami, Kousei; Nakayama, Tomohiro; Ushijima, Yasuhiro; Kakihara, Daisuke; Takayama, Yukihisa; Morita, Koichiro; Ishimatsu, Keisuke; Takao, Seiichiro; Yoshizumi, Tomoharu; Furusyo, Norihiro; Honda, Hiroshi.
Afiliação
  • Fujita N; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Nishie A; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Asayama Y; Department of Advanced Imaging and Interventional Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Ishigami K; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Nakayama T; Department of Molecular Imaging & Diagnosis, Graduate School of Medical Sciences, Kyushu University.
  • Ushijima Y; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Kakihara D; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Takayama Y; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Morita K; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Ishimatsu K; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Takao S; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
  • Yoshizumi T; Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University.
  • Furusyo N; Department of General Internal Medicine, Graduate School of Medical Sciences, Kyushu University.
  • Honda H; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
Magn Reson Med Sci ; 19(4): 389-393, 2020 Dec 01.
Article em En | MEDLINE | ID: mdl-32051362
ABSTRACT
We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Hepacivirus / Hepatite C Crônica / Gadolínio DTPA / Fígado Tipo de estudo: Observational_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Hepacivirus / Hepatite C Crônica / Gadolínio DTPA / Fígado Tipo de estudo: Observational_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article