TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise.

Liu, Yang; Nguyen, Phong T; Wang, Xun; Zhao, Yuting; Meacham, Corbin E; Zou, Zhongju; Bordieanu, Bogdan; Johanns, Manuel; Vertommen, Didier; Wijshake, Tobias; May, Herman; Xiao, Guanghua; Shoji-Kawata, Sanae; Rider, Mark H; Morrison, Sean J; Mishra, Prashant; Levine, Beth

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise.

Liu, Yang; Nguyen, Phong T; Wang, Xun; Zhao, Yuting; Meacham, Corbin E; Zou, Zhongju; Bordieanu, Bogdan; Johanns, Manuel; Vertommen, Didier; Wijshake, Tobias; May, Herman; Xiao, Guanghua; Shoji-Kawata, Sanae; Rider, Mark H; Morrison, Sean J; Mishra, Prashant; Levine, Beth.

Afiliação

Liu Y; Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. yang.liu3@utsouthwestern.edu.
Nguyen PT; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA. yang.liu3@utsouthwestern.edu.
Wang X; Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Zhao Y; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Meacham CE; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Zou Z; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Bordieanu B; Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Johanns M; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Vertommen D; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Wijshake T; Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
May H; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Xiao G; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Shoji-Kawata S; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Rider MH; De Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
Morrison SJ; De Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
Mishra P; Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Levine B; Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature ; 578(7796): 605-609, 2020 02.

Article em En | MEDLINE | ID: mdl-32051584

Assuntos

Proteínas Quinases Ativadas por AMP/metabolismo; Proteína Beclina-1/metabolismo; Músculo Esquelético/metabolismo; Condicionamento Físico Animal/fisiologia; Receptor Toll-Like 9/metabolismo; Animais; Autofagia; Ativação Enzimática; Exercício Físico; Glucose/metabolismo; Humanos; Masculino; Camundongos; Modelos Animais; Músculo Esquelético/enzimologia; Fosfatidilinositol 3-Quinase/metabolismo; Receptor Toll-Like 9/deficiência; Receptor Toll-Like 9/genética; Proteínas Supressoras de Tumor/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Condicionamento Físico Animal / Músculo Esquelético / Receptor Toll-Like 9 / Proteínas Quinases Ativadas por AMP / Proteína Beclina-1 Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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