Efficacy and safety of topical sofpironium bromide gel for the treatment of axillary hyperhidrosis: A phase II, randomized, controlled, double-blinded trial.

Kirsch, Brandon; Smith, Stacy; Cohen, Joel; DuBois, Janet; Green, Lawrence; Baumann, Leslie; Bhatia, Neal; Pariser, David; Liu, Ping-Yu; Chadha, Deepak; Walker, Patricia

Kirsch, Brandon; Smith, Stacy; Cohen, Joel; DuBois, Janet; Green, Lawrence; Baumann, Leslie; Bhatia, Neal; Pariser, David; Liu, Ping-Yu; Chadha, Deepak; Walker, Patricia.

Afiliação

Kirsch B; Brickell Biotech, Inc, Boulder, Colorado.
Smith S; California Dermatology and Clinical Research Institute, Encinitas, California.
Cohen J; AboutSkin Dermatology and DermSurgery, Greenwood Village, Colorado; Department of Dermatology, University of California, Irvine, California.
DuBois J; DermResearch Inc, Austin, Texas.
Green L; Department of Dermatology, George Washington University School of Medicine, Washington, DC.
Baumann L; Baumann Cosmetic and Research Institute, Miami, Florida.
Bhatia N; Therapeutics Clinical Research, San Diego, California.
Pariser D; Department of Dermatology, Eastern Virginia Medical School and Virginia Clinical Research, Inc, Norfolk, Virginia.
Liu PY; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Chadha D; Brickell Biotech, Inc, Boulder, Colorado. Electronic address: dchadha@brickellbio.com.
Walker P; Brickell Biotech, Inc, Boulder, Colorado.

J Am Acad Dermatol ; 82(6): 1321-1327, 2020 Jun.

Article em En | MEDLINE | ID: mdl-32068049

Assuntos

Antagonistas Colinérgicos/uso terapêutico; Hiperidrose/tratamento farmacológico; Adulto; Axila; Antagonistas Colinérgicos/efeitos adversos; Método Duplo-Cego; Feminino; Géis; Glicopirrolato/análogos & derivados; Humanos; Masculino; Pessoa de Meia-Idade; Índice de Gravidade de Doença; Suor/metabolismo; Transtornos da Visão/induzido quimicamente; Xerostomia/induzido quimicamente; Adulto Jovem

Palavras-chave

HDSM-Ax; anticholinergic; axillary hyperhidrosis; retrometabolic drug; sofpironium bromide; topical

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antagonistas Colinérgicos / Hiperidrose Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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