Steatohepatitis due to FOLFIRINOX regimen in adjuvant pancreas cancer treatment mimicking liver metastasis.
J Oncol Pharm Pract
; 26(7): 1738-1742, 2020 Oct.
Article
em En
| MEDLINE
| ID: mdl-32070199
ABSTRACT
INTRODUCTION:
The combination of fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) is more toxic than gemcitabine, but it is a safe regimen with manageable toxicities. CASE REPORT We report a case with steatohepatitis mimicking liver metastasis as toxicity that was not seen in study patient population.Management andoutcome:
In the adjuvant statement with FOLFIRINOX due to biopsy, we give the same regimen by excluding metastasis.DISCUSSION:
The adverse events of drugs are important predictive factor for treatment management, as important as efficacy. Especially the new lesion and metastasis is the most important factor for changing treatment. The clinicians must be careful about adverse events of regimens.CONCLUSION:
FOLFIRINOX regimen is the most important combination in pancreas cancer adjuvant setting. This case shows us the different presentation of usual adverse event.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Protocolos de Quimioterapia Combinada Antineoplásica
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Fígado Gorduroso
/
Neoplasias Hepáticas
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article