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Update on chronic intestinal pseudo-obstruction.
Zenzeri, Letizia; Tambucci, Renato; Quitadamo, Paolo; Giorgio, Valentina; De Giorgio, Roberto; Di Nardo, Giovanni.
Afiliação
  • Zenzeri L; Emergency Pediatric Department, Santobono-Pausilipon Children's Hospital, Naples.
  • Tambucci R; Digestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome.
  • Quitadamo P; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila.
  • Giorgio V; Department of Pediatrics, Santobono-Pausilipon Children's Hospital, Naples.
  • De Giorgio R; Department of Pediatrics, Catholic University, Rome.
  • Di Nardo G; Department of Medical Sciences, University of Ferrara, Ferrara.
Curr Opin Gastroenterol ; 36(3): 230-237, 2020 05.
Article em En | MEDLINE | ID: mdl-32073506
PURPOSE OF REVIEW: Chronic intestinal pseudo-obstruction (CIPO) is the most severe and disabling form of gastrointestinal dysmotility characterized by an impairment of coordinated propulsive activity in the gastrointestinal tract mimicking mechanical intestinal obstruction. Over the last few years, major advances have been made in the diagnostic and therapeutic management of this rare disorder. RECENT FINDINGS: The present narrative review aims to summarize the current literature about the management of CIPO focusing on significant novelties about definition, epidemiology, diagnosis, and therapeutic options. The most significant advancement is a consensus on classification and dedicated diagnostic criteria for CIPO in children highlighting the distinctive features between adult and pediatric forms of CIPO (hence pediatric intestinal pseudo-obstruction). Despite no single diagnostic test is pathognomonic of CIPO and no recommended drug treatment is advised to improve gastrointestinal motility, recent reports suggest promising results in both diagnostic testing and therapy that might assist the diagnosis and help the management of patients with CIPO. SUMMARY: The articles referenced in this review will help in optimizing the clinical management of this rare and severe disease in adult population.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudo-Obstrução Intestinal Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudo-Obstrução Intestinal Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article