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Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Laitakari, Anna; Huttunen, Riikka; Kuvaja, Paula; Hannuksela, Pauliina; Szabo, Zoltan; Heikkilä, Minna; Kerkelä, Risto; Myllyharju, Johanna; Dimova, Elitsa Y; Serpi, Raisa; Koivunen, Peppi.
Afiliação
  • Laitakari A; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Huttunen R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Kuvaja P; Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland.
  • Hannuksela P; Department of Pathology, Oulu University Hospital, Oulu, Finland.
  • Szabo Z; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Heikkilä M; Research Unit of Biomedicine, Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland.
  • Kerkelä R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Myllyharju J; Research Unit of Biomedicine, Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland.
  • Dimova EY; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Serpi R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Koivunen P; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
FASEB J ; 34(4): 5590-5609, 2020 04.
Article em En | MEDLINE | ID: mdl-32100354
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Prolina Dioxigenases do Fator Induzível por Hipóxia / Inflamação / Nefropatias / Hepatopatias / Neoplasias Hepáticas Experimentais Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Prolina Dioxigenases do Fator Induzível por Hipóxia / Inflamação / Nefropatias / Hepatopatias / Neoplasias Hepáticas Experimentais Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article