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Development, synthesis and biological investigation of a novel class of potent PC-PLC inhibitors.
Pilkington, Lisa I; Sparrow, Kevin; Rees, Shaun W P; Paulin, Emily K; van Rensburg, Michelle; Xu, Chris Sun; Langley, Ries J; Leung, Ivanhoe K H; Reynisson, Jóhannes; Leung, Euphemia; Barker, David.
Afiliação
  • Pilkington LI; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Sparrow K; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Rees SWP; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Paulin EK; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • van Rensburg M; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Xu CS; Auckland Cancer Society Research Centre, University of Auckland, Grafton, Auckland, 1023, New Zealand.
  • Langley RJ; School of Medical Sciences, University of Auckland, Auckland, 1023, New Zealand.
  • Leung IKH; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Reynisson J; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand; School of Pharmacy, Keele University, Hornbeam Building, Staffordshire, ST5 5BG, United Kingdom.
  • Leung E; Auckland Cancer Society Research Centre, University of Auckland, Grafton, Auckland, 1023, New Zealand.
  • Barker D; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand; MacDiarmid Institute for Advanced Materials and Nanotechnology, Wellington, New Zealand. Electronic address: d.barker@auckland.ac.nz.
Eur J Med Chem ; 191: 112162, 2020 Apr 01.
Article em En | MEDLINE | ID: mdl-32101781
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfolipases Tipo C / Tionas / Hidrocarbonetos Aromáticos com Pontes / Inibidores Enzimáticos / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfolipases Tipo C / Tionas / Hidrocarbonetos Aromáticos com Pontes / Inibidores Enzimáticos / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article