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Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice.
Spieler, Derek; Namendorf, Christian; Namendorf, Tamara; von Cube, Maja; Uhr, Manfred.
Afiliação
  • Spieler D; Department of Psychosomatic Medicine and Psychotherapy, Center for Mental Health, Faculty of Medicine, Albert-Ludwigs-Universität Freiburg, Hauptstraße 8, 79104, Freiburg, Germany; Helmholtz Zentrum München, Institute of Epidemiology, Mental Health Research Unit, German Research Center for Environme
  • Namendorf C; Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, 80804, Munich, Germany. Electronic address: chnamen@psych.mpg.de.
  • Namendorf T; Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, 80804, Munich, Germany. Electronic address: gerlach@psych.mpg.de.
  • von Cube M; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Straße 26, 79104, Freiburg, Germany. Electronic address: cube@imbi.uni-freiburg.de.
  • Uhr M; Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, 80804, Munich, Germany. Electronic address: uhr@psych.mpg.de.
J Psychiatr Res ; 124: 29-33, 2020 05.
Article em En | MEDLINE | ID: mdl-32114029
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article