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Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López, Saioa; Lim, Emilia L; Horswell, Stuart; Haase, Kerstin; Huebner, Ariana; Dietzen, Michelle; Mourikis, Thanos P; Watkins, Thomas B K; Rowan, Andrew; Dewhurst, Sally M; Birkbak, Nicolai J; Wilson, Gareth A; Van Loo, Peter; Jamal-Hanjani, Mariam; Swanton, Charles; McGranahan, Nicholas.
Afiliação
  • López S; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.
  • Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Horswell S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Haase K; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute and University College London Cancer Institute, London, UK.
  • Huebner A; Bioinformatics and Biostatistics Group, Francis Crick Institute, London, UK.
  • Dietzen M; Cancer Genomics Laboratory, Francis Crick Institute, London, UK.
  • Mourikis TP; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.
  • Watkins TBK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Rowan A; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute and University College London Cancer Institute, London, UK.
  • Dewhurst SM; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.
  • Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Wilson GA; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute and University College London Cancer Institute, London, UK.
  • Van Loo P; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.
  • Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Swanton C; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute and University College London Cancer Institute, London, UK.
  • McGranahan N; Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, NY, USA.
Nat Genet ; 52(3): 283-293, 2020 03.
Article em En | MEDLINE | ID: mdl-32139907
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Genoma Humano / Carcinoma Pulmonar de Células não Pequenas / Duplicação Gênica / Proteínas Supressoras de Tumor / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Genoma Humano / Carcinoma Pulmonar de Células não Pequenas / Duplicação Gênica / Proteínas Supressoras de Tumor / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article