6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis.

Hoshino, Tomonori; Matsuzawa, Shu-Ichi; Takahashi, Ryosuke

Hoshino, Tomonori; Matsuzawa, Shu-Ichi; Takahashi, Ryosuke.

Afiliação

Hoshino T; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
Matsuzawa SI; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan. Electronic address: smatsuza@kuhp.kyoto-u.ac.jp.
Takahashi R; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan. Electronic address: ryosuket@kuhp.kyoto-u.ac.jp.

Neurosci Res ; 163: 43-51, 2021 Feb.

Article em En | MEDLINE | ID: mdl-32145212

Assuntos

Esclerose Lateral Amiotrófica; Esclerose Lateral Amiotrófica/tratamento farmacológico; Animais; Morte Celular; Modelos Animais de Doenças; Hipóxia/complicações; Hipóxia/tratamento farmacológico; Camundongos; Camundongos Transgênicos; Neurônios Motores; Piranos; Superóxido Dismutase; Superóxido Dismutase-1; Xantenos

Palavras-chave

6-Deoxyjacareubin; Amyotrophic lateral sclerosis; Cell death; Cu/Zn superoxide dismutase; Hypoxia; Neurodegeneration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Lateral Amiotrófica Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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