The efficacy and safety of multiple-dose intravenous tranexamic acid in reducing perioperative blood loss in patients with thoracolumbar burst fracture.

Wang, Feng; Nan, Liping; Feng, Xinmin; Wang, Yongxiang; Yang, Jiandong; Tao, Yuping; Cheng, Xiaofei; Zhang, Shengfei; Zhang, Liang

Wang, Feng; Nan, Liping; Feng, Xinmin; Wang, Yongxiang; Yang, Jiandong; Tao, Yuping; Cheng, Xiaofei; Zhang, Shengfei; Zhang, Liang.

Afiliação

Wang F; Department of Orthopedics, Dalian Medical University, Dalian, 116000, China; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Nan L; Department of Orthopedics, Dalian Medical University, Dalian, 116000, China; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Feng X; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Wang Y; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Yang J; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Tao Y; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Cheng X; Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Orthopaedic Implants, Shanghai, 200011, China.
Zhang S; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China.
Zhang L; Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou, 225001, China. Electronic address: zhangliang6320@sina.com.

Clin Neurol Neurosurg ; 193: 105766, 2020 06.

Article em En | MEDLINE | ID: mdl-32146231

Assuntos

Antifibrinolíticos/uso terapêutico; Perda Sanguínea Cirúrgica/prevenção & controle; Fixação Interna de Fraturas/métodos; Procedimentos Neurocirúrgicos/métodos; Fraturas da Coluna Vertebral/cirurgia; Ácido Tranexâmico/uso terapêutico; Administração Intravenosa; Adulto; Antifibrinolíticos/efeitos adversos; Transfusão de Sangue; Proteína C-Reativa/análise; Estudos de Coortes; Feminino; Hemoglobinas/análise; Humanos; Interleucina-6/sangue; Vértebras Lombares/lesões; Vértebras Lombares/cirurgia; Masculino; Pessoa de Meia-Idade; Parafusos Pediculares; Estudos Retrospectivos; Vértebras Torácicas/lesões; Vértebras Torácicas/cirurgia; Ácido Tranexâmico/efeitos adversos

Palavras-chave

Inflammation response; Perioperative blood loss; Prethrombotic state molecular marks; Thoracolumbar burst fracture; Tranexamic acid; Wiltse approach

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Tranexâmico / Perda Sanguínea Cirúrgica / Fraturas da Coluna Vertebral / Procedimentos Neurocirúrgicos / Fixação Interna de Fraturas / Antifibrinolíticos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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