PIMMS43 is required for malaria parasite immune evasion and sporogonic development in the mosquito vector.

Ukegbu, Chiamaka V; Giorgalli, Maria; Tapanelli, Sofia; Rona, Luisa D P; Jaye, Amie; Wyer, Claudia; Angrisano, Fiona; Blagborough, Andrew M; Christophides, George K; Vlachou, Dina

Ukegbu, Chiamaka V; Giorgalli, Maria; Tapanelli, Sofia; Rona, Luisa D P; Jaye, Amie; Wyer, Claudia; Angrisano, Fiona; Blagborough, Andrew M; Christophides, George K; Vlachou, Dina.

Afiliação

Ukegbu CV; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Giorgalli M; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Tapanelli S; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Rona LDP; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Jaye A; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Wyer C; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Angrisano F; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Blagborough AM; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Christophides GK; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom g.christophides@imperial.ac.uk d.vlachou@imperial.ac.uk.
Vlachou D; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom g.christophides@imperial.ac.uk d.vlachou@imperial.ac.uk.

Proc Natl Acad Sci U S A ; 117(13): 7363-7373, 2020 03 31.

Article em En | MEDLINE | ID: mdl-32165544

Assuntos

Anopheles/imunologia; Mosquitos Vetores/imunologia; Plasmodium falciparum/imunologia; Proteínas de Protozoários/imunologia; Animais; Anopheles/metabolismo; Anopheles/parasitologia; Feminino; Interações Hospedeiro-Parasita/imunologia; Humanos; Evasão da Resposta Imune; Malária Falciparum/parasitologia; Malária Falciparum/transmissão; Mosquitos Vetores/metabolismo; Mosquitos Vetores/parasitologia; Oocistos/imunologia; Plasmodium falciparum/metabolismo; Proteínas de Protozoários/metabolismo; Esporozoítos/imunologia

Palavras-chave

complement-like response; malaria transmission; mosquito innate immunity; mosquito population replacement; transmission blocking vaccines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Mosquitos Vetores / Anopheles Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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