Oxidative Stress Down-Regulates MiR-20b-5p, MiR-106a-5p and E2F1 Expression to Suppress the G1/S Transition of the Cell Cycle in Multipotent Stromal Cells.

Tai, Lihui; Huang, Chiu-Jung; Choo, Kong Bung; Cheong, Soon Keng; Kamarul, Tunku

Tai, Lihui; Huang, Chiu-Jung; Choo, Kong Bung; Cheong, Soon Keng; Kamarul, Tunku.

Afiliação

Tai L; Centre for Stem Cell Research, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Huang CJ; Postgraduate Program, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Choo KB; Department of Animal Science & Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan.
Cheong SK; Centre for Stem Cell Research, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Kamarul T; Department of Preclinical Sciences, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.

Int J Med Sci ; 17(4): 457-470, 2020.

Article em En | MEDLINE | ID: mdl-32174776

Assuntos

Fator de Transcrição E2F1/metabolismo; MicroRNAs/metabolismo; Estresse Oxidativo/fisiologia; Western Blotting; Ciclo Celular/efeitos dos fármacos; Linhagem Celular; Fator de Transcrição E2F1/genética; Humanos; Peróxido de Hidrogênio/farmacologia; MicroRNAs/genética; Estresse Oxidativo/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa

Palavras-chave

E2F1; G1/S transition of cell cycle; miR-17 family; miR-20b-5p & miR-106a-5p; oxidative stress; p21/CDK/E2F1 pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / MicroRNAs / Fator de Transcrição E2F1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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