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Guselkumab in biologic-naive patients with active psoriatic arthritis (DISCOVER-2): a double-blind, randomised, placebo-controlled phase 3 trial.
Mease, Philip J; Rahman, Proton; Gottlieb, Alice B; Kollmeier, Alexa P; Hsia, Elizabeth C; Xu, Xie L; Sheng, Shihong; Agarwal, Prasheen; Zhou, Bei; Zhuang, Yanli; van der Heijde, Désirée; McInnes, Iain B.
Afiliação
  • Mease PJ; Department of Rheumatology, Swedish Medical Center, Providence St Joseph Health and University of Washington, Seattle, WA, USA. Electronic address: pmease@philipmease.com.
  • Rahman P; Department of Rheumatology, Memorial University of Newfoundland, St Johns, NL, Canada.
  • Gottlieb AB; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kollmeier AP; Immunology, Janssen Research and Development, San Diego, CA, USA.
  • Hsia EC; Immunology, Janssen Research and Development, Spring House, PA, USA.
  • Xu XL; Immunology, Janssen Research and Development, San Diego, CA, USA.
  • Sheng S; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Agarwal P; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Zhou B; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Zhuang Y; Clinical Pharmacology and Pharmacometrics, Janssen Research and Development, Spring House, PA, USA.
  • van der Heijde D; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • McInnes IB; Division of Immunology, University of Glasgow, Glasgow, UK.
Lancet ; 395(10230): 1126-1136, 2020 04 04.
Article em En | MEDLINE | ID: mdl-32178766

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Psoriásica / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Psoriásica / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article