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Transcriptome signature analysis repurposes trifluoperazine for the treatment of fragile X syndrome in mouse model.
Ding, Qi; Sethna, Ferzin; Wu, Xue-Ting; Miao, Zhuang; Chen, Ping; Zhang, Yueqi; Xiao, Hua; Feng, Wei; Feng, Yue; Li, Xuan; Wang, Hongbing.
Afiliação
  • Ding Q; Department of Physiology, Michigan State University, East Lansing, USA.
  • Sethna F; Genetics Program, Michigan State University, East Lansing, USA.
  • Wu XT; Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032, Shanghai, China.
  • Miao Z; Genetics Program, Michigan State University, East Lansing, USA.
  • Chen P; Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032, Shanghai, China.
  • Zhang Y; Department of Physiology, Michigan State University, East Lansing, USA.
  • Xiao H; Department of Physiology, Michigan State University, East Lansing, USA.
  • Feng W; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, 30322, Georgia.
  • Feng Y; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, 30322, Georgia.
  • Li X; Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032, Shanghai, China.
  • Wang H; Department of Physiology, Michigan State University, East Lansing, USA. wangho@msu.edu.
Commun Biol ; 3(1): 127, 2020 03 16.
Article em En | MEDLINE | ID: mdl-32179850
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trifluoperazina / Fosfotransferases (Aceptor do Grupo Álcool) / Perfilação da Expressão Gênica / Inibidores de Proteínas Quinases / Reposicionamento de Medicamentos / Transcriptoma / Síndrome do Cromossomo X Frágil / Hipocampo / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trifluoperazina / Fosfotransferases (Aceptor do Grupo Álcool) / Perfilação da Expressão Gênica / Inibidores de Proteínas Quinases / Reposicionamento de Medicamentos / Transcriptoma / Síndrome do Cromossomo X Frágil / Hipocampo / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article