Tumor necrosis factor &#945; in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity.

Ding, Li; Ning, Hong-Mei; Li, Pei-Lin; Yan, Hong-Min; Han, Dong-Mei; Zheng, Xiao-Li; Liu, Jing; Zhu, Ling; Xue, Mei; Mao, Ning; Guo, Zi-Kuan; Zhu, Heng; Wang, Heng-Xiang

Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity.

Ding, Li; Ning, Hong-Mei; Li, Pei-Lin; Yan, Hong-Min; Han, Dong-Mei; Zheng, Xiao-Li; Liu, Jing; Zhu, Ling; Xue, Mei; Mao, Ning; Guo, Zi-Kuan; Zhu, Heng; Wang, Heng-Xiang.

Afiliação

Ding L; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Ning HM; Beijing Institute of Radiation Medicine, Road Taiping 27, Beijing, 100850, People's Republic of China.
Li PL; The Fifth Medical Center of Chinese PLA General Hospital, East Street 8, Beijing, 100071, People's Republic of China.
Yan HM; Beijing Institute of Radiation Medicine, Road Taiping 27, Beijing, 100850, People's Republic of China.
Han DM; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Zheng XL; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Liu J; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Zhu L; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Xue M; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Mao N; Medical Center of Air Forces, PLA, Road Fucheng 30, Beijing, 100142, People's Republic of China.
Guo ZK; Beijing Institute of Basic Medical Sciences, Road Taiping 27, Beijing, 100850, People's Republic of China.
Zhu H; Beijing Institute of Radiation Medicine, Road Taiping 27, Beijing, 100850, People's Republic of China. guozikuankz@sina.com.
Wang HX; Beijing Institute of Radiation Medicine, Road Taiping 27, Beijing, 100850, People's Republic of China. zhudingdingabc@163.com.

Stem Cell Res Ther ; 11(1): 119, 2020 03 17.

Article em En | MEDLINE | ID: mdl-32183881

Assuntos

Doença Enxerto-Hospedeiro; Células-Tronco Mesenquimais; Medula Óssea; Células da Medula Óssea; Hematopoese; Humanos; Fator de Necrose Tumoral alfa/genética

Palavras-chave

Acute graft versus host disease; Bone marrow niche; Mesenchymal stem cell; Stemness; Tumor necrosis factor-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais / Doença Enxerto-Hospedeiro Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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