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Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization.
Liu, Zhaoqi; Yoshimi, Akihide; Wang, Jiguang; Cho, Hana; Chun-Wei Lee, Stanley; Ki, Michelle; Bitner, Lillian; Chu, Timothy; Shah, Harshal; Liu, Bo; Mato, Anthony R; Ruvolo, Peter; Fabbri, Giulia; Pasqualucci, Laura; Abdel-Wahab, Omar; Rabadan, Raul.
Afiliação
  • Liu Z; Program for Mathematical Genomics, Columbia University, New York, New York.
  • Yoshimi A; Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, New York.
  • Wang J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. rr2579@cumc.columbia.edu yoshimia@mskcc.org.
  • Cho H; Division of Life Science, Department of Chemical and Biological Engineering, Center for Systems Biology and Human Health and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
  • Chun-Wei Lee S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ki M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Bitner L; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Chu T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Shah H; Program for Mathematical Genomics, Columbia University, New York, New York.
  • Liu B; Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, New York.
  • Mato AR; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ruvolo P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Fabbri G; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Pasqualucci L; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Abdel-Wahab O; Institute for Cancer Genetics, Columbia University, New York, New York.
  • Rabadan R; Institute for Cancer Genetics, Columbia University, New York, New York.
Cancer Discov ; 10(6): 806-821, 2020 06.
Article em En | MEDLINE | ID: mdl-32188705

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Transformação Celular Neoplásica / Carcinogênese / Fatores de Processamento de RNA / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Transformação Celular Neoplásica / Carcinogênese / Fatores de Processamento de RNA / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article