Analysis of Epidemiological and Clinical Features in Older Patients With Coronavirus Disease 2019 (COVID-19) Outside Wuhan.
Clin Infect Dis
; 71(15): 740-747, 2020 07 28.
Article
em En
| MEDLINE
| ID: mdl-32211844
ABSTRACT
BACKGROUND:
The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to public health in China, with high contagious capacity and varied mortality. This study aimed to investigate the epidemiological and clinical characteristics of older patients with COVID-19 outside Wuhan.METHODS:
A retrospective study was performed, with collecting data from medical records of confirmed COVID-19 patients in Zhejiang province from 17 January to 12 February 2020. Epidemiological, clinical, and treatment data were analyzed between older (≥ 60 years) and younger (< 60 years) patients.RESULTS:
A total of 788 patients with confirmed COVID-19 were selected; 136 were older patients with corresponding mean age of 68.28â ±â 7.31 years. There was a significantly higher frequency of women in older patient group compared with younger patients (57.35% vs 46.47%, Pâ =â .021). The presence of coexisting medical conditions was significantly higher in older patients compared with younger patients (55.15% vs 21.93%, Pâ <â .001), including the rate of hypertension, diabetes, heart disease, and chronic obstructive pulmonary disease. Significantly higher rates of severe clinical type (older vs younger groups 16.18% vs 5.98%, Pâ <â .001), critical clinical type (8.82% vs 0.77%, Pâ <â .001), shortness of breath (12.50% vs 3.07%, Pâ <â .001), and temperature of > 39.0°C (13.97% vs 7.21%, Pâ =â .010) were observed in older patients compared with younger patients. Finally, higher rates of intensive care unit admission (9.56% vs 1.38%, Pâ <â .001) and methylprednisolone application (28.68% vs 9.36%, Pâ <â .001) were also identified in older patients compared with younger ones.CONCLUSIONS:
The specific epidemiological and clinical features of older COVID-19 patients included significantly higher female sex, body temperature, comorbidities, and rate of severe and critical type disease.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Infecções por Coronavirus
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article