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[Effect of saw palmetto extract on the reproductive function of male rats with chronic prostatitis].
Zhan, Xu-Xin; Mo, Dun-Sheng; Cai, Hong-Cai; Xue, Song; Shang, Xue-Jun.
Afiliação
  • Zhan XX; Department of Reproductive Medicine, Xi'an No. 4 Hospital, Xi'an, Shaanxi 710004, China.
  • Mo DS; Department of Urology, Liuzhou Workers' Hospital / The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi 545005, China.
  • Cai HC; Family Planning Research Institute / Center of Reproductive Medicine, Huazhong University of Science and Technology, Wuhan Hubei 430030, China.
  • Xue S; Department of Urology, Nanjing School of Clinical Medicine, Southern Medical University / General Hospital of Eastern Theater Command, Nanjing, Jiangsu 210002, China.
  • Shang XJ; Department of Andrology, Nanjing School of Clinical Medicine, Southern Medical University / General Hospital of Eastern Theater Command, Nanjing, Jiangsu 210002, China.
Zhonghua Nan Ke Xue ; 25(5): 399-402, 2019 May.
Article em Zh | MEDLINE | ID: mdl-32216223
OBJECTIVE: To investigate the effect of saw palmetto extract (SPE) on the reproductive function of rats with chronic prostatitis (CP). METHODS: Forty male SD rats were equally randomized into groups A (blank control), B (blank control + SPE, C (CP model control) and D (CP model + SPE), and the CP model was made by injection of 1% λ-carrageenan solution into the prostate. The animals in groups A and C were gavaged with normal saline while those in groups B and D with SPE at 0.10 g/kg/d, all for 30 successive days. After drug withdrawal, the rats were mated with female ones in the ratio of 1∶1) and sacrificed 7 days later, their bilateral epididymides collected for detection of sperm count and motility. The numbers of pregnancies and fetuses were recorded and compared among different groups. RESULTS: Compared with the rats in group A, those in group C showed a marked decrease in epididymal sperm motility (ï¼»68.01 ± 1.80ï¼½% vs ï¼»62.59 ± 4.82ï¼½%, P < 0.05), but those in groups B and D exhibited no statistically significant difference (ï¼»67.69 ± 4.06ï¼½% and ï¼»67.93 ± 3.39ï¼½%, P > 0.05). There were no statistically significant differences in the count of epididymal sperm, rate of pregnancy and number of fetuses between group A and the other groups (P > 0.05). CONCLUSIONS: SPE can improve the semen parameters of CP rats, and has no adverse effect on the rate of pregnancy and number of fetuses.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prostatite / Contagem de Espermatozoides / Motilidade dos Espermatozoides / Extratos Vegetais Limite: Animals Idioma: Zh Ano de publicação: 2019 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prostatite / Contagem de Espermatozoides / Motilidade dos Espermatozoides / Extratos Vegetais Limite: Animals Idioma: Zh Ano de publicação: 2019 Tipo de documento: Article