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Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
Wang, Zhaohui; Xu, Cheng; Diplas, Bill H; Moure, Casey J; Chen, Chin-Pu Jason; Chen, Lee H; Du, Changzheng; Zhu, Huishan; Greer, Paula K; Zhang, Liwei; He, Yiping; Waitkus, Matthew S; Yan, Hai.
Afiliação
  • Wang Z; Department of Pathology, Duke University, Durham, North Carolina.
  • Xu C; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Diplas BH; Department of Pathology, Duke University, Durham, North Carolina.
  • Moure CJ; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Chen CJ; Department of Pathology, Duke University, Durham, North Carolina.
  • Chen LH; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Du C; Department of Pathology, Duke University, Durham, North Carolina.
  • Zhu H; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Greer PK; Department of Pathology, Duke University, Durham, North Carolina.
  • Zhang L; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • He Y; Department of Pathology, Duke University, Durham, North Carolina.
  • Waitkus MS; Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Yan H; Department of Pathology, Duke University, Durham, North Carolina.
Mol Cancer Res ; 18(7): 968-980, 2020 07.
Article em En | MEDLINE | ID: mdl-32229503
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Neoplasias do Tronco Encefálico / Dipeptídeos / Proteína Fosfatase 2C / Glioma Pontino Intrínseco Difuso / Aminopiridinas / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Neoplasias do Tronco Encefálico / Dipeptídeos / Proteína Fosfatase 2C / Glioma Pontino Intrínseco Difuso / Aminopiridinas / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article