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Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
Clarke, Matthew; Mackay, Alan; Ismer, Britta; Pickles, Jessica C; Tatevossian, Ruth G; Newman, Scott; Bale, Tejus A; Stoler, Iris; Izquierdo, Elisa; Temelso, Sara; Carvalho, Diana M; Molinari, Valeria; Burford, Anna; Howell, Louise; Virasami, Alex; Fairchild, Amy R; Avery, Aimee; Chalker, Jane; Kristiansen, Mark; Haupfear, Kelly; Dalton, James D; Orisme, Wilda; Wen, Ji; Hubank, Michael; Kurian, Kathreena M; Rowe, Catherine; Maybury, Mellissa; Crosier, Stephen; Knipstein, Jeffrey; Schüller, Ulrich; Kordes, Uwe; Kram, David E; Snuderl, Matija; Bridges, Leslie; Martin, Andrew J; Doey, Lawrence J; Al-Sarraj, Safa; Chandler, Christopher; Zebian, Bassel; Cairns, Claire; Natrajan, Rachael; Boult, Jessica K R; Robinson, Simon P; Sill, Martin; Dunkel, Ira J; Gilheeney, Stephen W; Rosenblum, Marc K; Hughes, Debbie; Proszek, Paula Z; Macdonald, Tobey J.
Afiliação
  • Clarke M; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Mackay A; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Ismer B; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pickles JC; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Tatevossian RG; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Newman S; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Bale TA; Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Stoler I; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Izquierdo E; Department of Neuropathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
  • Temelso S; Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.
  • Carvalho DM; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Molinari V; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Burford A; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Howell L; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Virasami A; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Fairchild AR; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.
  • Avery A; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Chalker J; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Kristiansen M; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Haupfear K; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Dalton JD; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
  • Orisme W; Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Wen J; Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Hubank M; Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Kurian KM; Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Rowe C; Molecular Diagnostics, Royal Marsden Hospital NHS Trust, Sutton, United Kingdom.
  • Maybury M; Brain Tumour Research Centre, University of Bristol, Bristol, United Kingdom.
  • Crosier S; Brain Tumour Research Centre, University of Bristol, Bristol, United Kingdom.
  • Knipstein J; The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Australia.
  • Schüller U; Oncology Service, Queensland Children's Hospital, Brisbane, Australia.
  • Kordes U; Child Health Research Centre, The University of Queensland, South Brisbane, Australia.
  • Kram DE; Newcastle Hospitals NHS Foundation Trust, Newcastle, United Kingdom.
  • Snuderl M; Division of Pediatric Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, Wisconsin.
  • Bridges L; Department of Neuropathology, University Hospital Hamburg-Eppendorf, and Research Institute Children's Cancer Center, Hamburg, Germany.
  • Martin AJ; Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
  • Doey LJ; Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
  • Al-Sarraj S; Section of Pediatric Hematology-Oncology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
  • Chandler C; Department of Neuropathology, NYU Langone Health, New York, New York.
  • Zebian B; Department of Neuropathology, St George's Hospital NHS Trust, London, United Kingdom.
  • Cairns C; Department of Neurosurgery, St George's Hospital NHS Trust, London, United Kingdom.
  • Natrajan R; Department of Clinical Neuropathology, Kings College Hospital NHS Trust, London, United Kingdom.
  • Boult JKR; Department of Clinical Neuropathology, Kings College Hospital NHS Trust, London, United Kingdom.
  • Robinson SP; Department of Neurosurgery, Kings College Hospital NHS Trust, London, United Kingdom.
  • Sill M; Department of Neurosurgery, Kings College Hospital NHS Trust, London, United Kingdom.
  • Dunkel IJ; Department of Neurosurgery, Kings College Hospital NHS Trust, London, United Kingdom.
  • Gilheeney SW; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom.
  • Rosenblum MK; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.
  • Hughes D; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.
  • Proszek PZ; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Macdonald TJ; Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York.
Cancer Discov ; 10(7): 942-963, 2020 07.
Article em En | MEDLINE | ID: mdl-32238360
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fusão Gênica / Glioma Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans / Infant Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fusão Gênica / Glioma Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans / Infant Idioma: En Ano de publicação: 2020 Tipo de documento: Article