Lnc-Ang362 is a pro-fibrotic long non-coding RNA promoting cardiac fibrosis after myocardial infarction by suppressing Smad7.

Chen, Guo; Huang, Sihui; Song, Feier; Zhou, Yingling; He, Xuyu

Chen, Guo; Huang, Sihui; Song, Feier; Zhou, Yingling; He, Xuyu.

Afiliação

Chen G; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. Electronic address: chenguo021@126.com.
Huang S; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; The Second School of Clinical Medicine, Southern Medical University
Song F; Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. Electronic address: feiersong@126.com.
Zhou Y; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. Electronic address: zylgdh@163.com.
He X; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. Electronic address: hexuyusci@163.com.

Arch Biochem Biophys ; 685: 108354, 2020 05 30.

Article em En | MEDLINE | ID: mdl-32240638

Assuntos

Fibrose/metabolismo; Infarto do Miocárdio/complicações; Miocárdio/metabolismo; RNA Longo não Codificante/metabolismo; Proteína Smad7/metabolismo; Animais; Sequência de Bases; Colágeno/metabolismo; Regulação para Baixo; Fibrose/etiologia; Masculino; Ratos Sprague-Dawley; Fator de Crescimento Transformador beta1/metabolismo; Regulação para Cima

Palavras-chave

Cardiac fibrosis; Long non-coding RNA; Myocardial infarction; Smad7; Transforming growth factor-ß1

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose / Proteína Smad7 / RNA Longo não Codificante / Infarto do Miocárdio / Miocárdio Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google