Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

Namekata, Kazuhiko; Guo, Xiaoli; Kimura, Atsuko; Azuchi, Yuriko; Kitamura, Yuta; Harada, Chikako; Harada, Takayuki

Namekata, Kazuhiko; Guo, Xiaoli; Kimura, Atsuko; Azuchi, Yuriko; Kitamura, Yuta; Harada, Chikako; Harada, Takayuki.

Afiliação

Namekata K; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Guo X; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Kimura A; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Azuchi Y; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Kitamura Y; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Harada C; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Harada T; Visual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan harada-tk@igakuken.or.jp.

J Biol Chem ; 295(19): 6710-6720, 2020 05 08.

Article em En | MEDLINE | ID: mdl-32241915

Assuntos

Fatores de Troca do Nucleotídeo Guanina/metabolismo; Esclerose Múltipla/metabolismo; Animais; Astrócitos/patologia; Modelos Animais de Doenças; Camundongos; Microglia/patologia; Esclerose Múltipla/patologia

Palavras-chave

DOCK10; DOCK11; DOCK9; astrocyte; gene knockout; guanine nucleotide exchange factor (GEF); microglia; migration; neurodegeneration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Troca do Nucleotídeo Guanina / Esclerose Múltipla Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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