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Cortical presentation of language functions in patients after total laryngectomy: a fMRI study.
Wypych, Aleksandra; Wierzchowska, Malgorzata; Burduk, Pawel; Zawada, Elzbieta; Nadolska, Katarzyna; Serafin, Zbigniew.
Afiliação
  • Wypych A; The Interdisciplinary Center for Modern Technologies, Nicolaus Copernicus University, Torun, Poland.
  • Wierzchowska M; Department of Otolaryngology, Oncology and Oral and Maxillofacial Surgery, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
  • Burduk P; Department of Otolaryngology, Oncology and Oral and Maxillofacial Surgery, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
  • Zawada E; Department of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
  • Nadolska K; Department of Geriatrics, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
  • Serafin Z; Department of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Neuroradiology ; 62(7): 843-849, 2020 Jul.
Article em En | MEDLINE | ID: mdl-32253455
ABSTRACT

PURPOSE:

The aim of this study is to use functional magnetic resonance (fMRI) to analyse the cortical presentation of selected language functions in patients after a total laryngectomy.

METHODS:

Eighteen patients after total laryngectomy treated with electrolarynx speech and 18 volunteers were included. The mean number of patients' post-operative speech rehabilitation sessions was five (range of 3-8 sessions). Four paradigms were used, including noun generation, pseudoword reading, reading phrases with pseudowords, and nonliteral sign reproduction.

RESULTS:

In noun, the most significant difference between the groups was the stronger activation of both lingual gyri in the volunteers. Pseudoword reading resulted in stronger activations in patients than in volunteers in the lingual gyri, the right cerebellum, the right Broca's area, and the right parietal operculum. Reading phrases with pseudowords involved different parts of the Brodmann area 40. During nonliteral sign reproduction, there was a stronger activation of the left Broca's area in volunteers and a stronger activation of the left premotor cortex in patients.

CONCLUSION:

This study provides evidence of altered cortical activation in response to language tasks in patients after a laryngectomy compared with healthy volunteers, which may be considered brain plasticity in response to a laryngectomy.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medida da Produção da Fala / Encéfalo / Imageamento por Ressonância Magnética / Laringectomia / Plasticidade Neuronal Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medida da Produção da Fala / Encéfalo / Imageamento por Ressonância Magnética / Laringectomia / Plasticidade Neuronal Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article