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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
Wang, Xiaobo; Cai, Bishuang; Yang, Xiaoming; Sonubi, Oluwatoni O; Zheng, Ze; Ramakrishnan, Rajasekhar; Shi, Hongxue; Valenti, Luca; Pajvani, Utpal B; Sandhu, Jaspreet; Infante, Rodney E; Radhakrishnan, Arun; Covey, Douglas F; Guan, Kun-Liang; Buck, Jochen; Levin, Lonny R; Tontonoz, Peter; Schwabe, Robert F; Tabas, Ira.
Afiliação
  • Wang X; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: xw2279@columbia.edu.
  • Cai B; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Yang X; Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia 750004, PRC.
  • Sonubi OO; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.
  • Zheng Z; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Ramakrishnan R; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Shi H; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Valenti L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano 20122, Italy; Translational Medicine - Transfusion Medicine and Hematology, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Milano 20122, Italy.
  • Pajvani UB; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Sandhu J; Department of Pathology and Laboratory Medicine, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90272, USA.
  • Infante RE; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Radhakrishnan A; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Covey DF; Department of Developmental Biology and Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Guan KL; Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
  • Buck J; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.
  • Levin LR; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.
  • Tontonoz P; Department of Pathology and Laboratory Medicine, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90272, USA.
  • Schwabe RF; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA; Institute of Human Nutrition, Columbia University, New York, NY 10032, USA.
  • Tabas I; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: iat1@columbia.edu.
Cell Metab ; 31(5): 969-986.e7, 2020 05 05.
Article em En | MEDLINE | ID: mdl-32259482
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Hepatócitos / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Adaptadoras de Transdução de Sinal / Hepatopatia Gordurosa não Alcoólica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Hepatócitos / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Adaptadoras de Transdução de Sinal / Hepatopatia Gordurosa não Alcoólica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article