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C-Glycosylation enabled by N-(glycosyloxy)acetamides.
Liu, Miao; Li, Bo-Han; Li, Tian; Wu, Xia; Liu, Meng; Xiong, De-Cai; Ye, Xin-Shan.
Afiliação
  • Liu M; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
  • Li BH; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
  • Li T; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
  • Wu X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
  • Liu M; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
  • Xiong DC; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
  • Ye XS; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. xinshan@bjmu.edu.cn decai@bjmu.edu.cn.
Org Biomol Chem ; 18(16): 3043-3046, 2020 04 29.
Article em En | MEDLINE | ID: mdl-32270159
ABSTRACT
The C-glycosylation of C-nucleophiles including allyltrimethylsilane, silyl enol ethers and phenols with N-(glycosyloxy)acetamides as glycosyl donors has been realized. This protocol provides a convenient and practical route for the synthesis of alkyl C-glycosides and aryl 2-deoxy-ß-C-glycosides under mild reaction conditions.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2020 Tipo de documento: Article